The tumor suppressor miRNAs include miR-30a and miR-101; miRNA-30a inhibits the activity of the autophagy gene Beclin-1 to prevent autophagic vesicle nucleation, while miR-101 suppresses the regulation of endocytosis by RAB5A and thereby affects autophagy body formation during the early stages of autophagosome formation [20]. The gene discussed is RAB5A; the disease is neoplasm.