ATM and neoplasm: Thus, Mapk7hemat−/−Atm−/− mice showed a significant increase in survival compared to Atm−/− mice (p = 0.02 at day 320, log-rank test), indicating that MAPK7 deficiency in the hematopoietic system delays death by spontaneous tumor development in Atm−/− mice and suggesting an antagonistic interaction between the MAPK7- and ATM-signaling pathways affecting thymic lymphoma development.