So, The result about the expression of either Lin28A or Lin28B in different lymph node metastasis stages showed that Lin28B protein level is significantly higher in patients with lymph node metastasis (N1 but not N2) than patients with non-lymph node metastasis (N0) (Figure 5B), whereas the Lin28A mRNA is significantly increased in patients with lymph node metastasis (N1 but not N2) than patients with non-lymph node metastasis (N0) (Figure 5D). This evidence concerns the gene LIN28A and metastatic malignant neoplasm in the lymph nodes.