As shown in Figure 2, both in PVI and non-PVI groups, IHC scores for Notch1 (116.81±25.57 and 72.22±35.53) were found increased compared to corresponding adjacent non-HCC tissues (49.99±21.63, P<0.001 and 0.001 respectively). The gene discussed is NOTCH1; the disease is hepatocellular carcinoma.