As hypothesized, the levels of inflammatory mediators (IL-6, CCL2, CCL3, CXCL1, CXCL10 and IFNα as expected) were lower in the blood and the spleen of Ifnar1-/- mice compared to WT counterparts at all times post-infection, except for IFNγ (Fig 2B). This evidence concerns the gene CXCL1 and infection.