PTPRN and type 1 diabetes mellitus: In addition, GIMAP expression is reduced in regulatory T cells of patients with type I diabetes 32, and a single nucleotide polymorphism in the polyadenylation signal of human Gimap5 is associated with IA‐2 autoantibody formation in patients with type I diabetes and predisposes individuals to systemic lupus erythematosus 33, 34.