DRD2 and Cognitive impairment: Disruption of hippocampal–PFC synchrony is associated with the cognitive deficits that occur in neuropsychiatric disorders such as schizophrenia (Dickerson et al., 2010, 2012; Sigurdsson et al., 2010), and D2R-dependent control of glutamatergic NMDAR neurotransmission has been particularly implicated in the regulation of hippocampal-PFC functional connectivity (Banks et al., 2015).