GPT and type 2 diabetes mellitus: For example, by exploiting the availability of serial 6-monthly liver function tests from the West of Scotland Coronary Prevention Study (WOSCOPS) (observational nested case control study, n = 946, 4.9 years follow-up), we noted that plasma levels of the liver enzyme alanine aminotransferase (ALT) and fasting triglyceride were the only significant independent predictors of the development of T2DM.