BRCA2 and cancer: This indicates that higher proliferative tumor cells are associated with higher expression levels of BRCA1, BRCA2, and RAD51. In addition, we examined the expression levels of these three genes in hereditary cancers with BRCA1/BRCA2 germline mutations versus sporadic cancers (from the Larsen et al. dataset [30]; 33 BRCA1-mutated cancers, 22 BRCA2- mutated cancers, and 128 sporadic cancers).