[38] In another study, tumor-derived MIF could recruit neutrophils via CXCR2-dependent chemotaxis and trigger the inflammatory activity by eliciting neutrophils’ release of C-C Motif Ligand 4 (CCL4) and matrix metalloprotease 9 (MMP9) in human hypopharyngeal carcinoma cell line FaDu. This evidence concerns the gene CXCR2 and neoplasm.