In the present study, we showed that the active TB population was diverse, presenting 13 HLA-DRB1 allelic groups with the highest frequency of HLA-DRB1*14 and HLA-DRB1*15 and the lowest frequency of HLA-DRB1*13 compared with healthy controls, as was also reported by some previous studies [43, 44]. Here, HLA-DRB1 is linked to tuberculosis.