To confirm whether IgG- and IgA-AECA recognize membrane proteins on HGEC, HGEC cells were incubated with serum of LN patients with high serum titer of IgG- or IgA-AECA and LN patients with low serum titer of IgG- or IgA-AECA. The gene discussed is CD79A; the disease is lobular neoplasia.