Interestingly, some of these functional and phenotypic features resemble those seen in sepsis.44, 45 In contrast with lymphocytes, which show an accelerated rate of apoptosis, neutrophil apoptosis is delayed in the course of sepsis.44, 45 Moreover, a reduced generation of ROS, an enhanced production of IL-8, and a high expression of CD11b and CD66b are usually found in neutrophils from septic patients.44, 45. The gene discussed is CXCL8; the disease is Sepsis.