As shown in Table 3, the overall OR showed that DAPK promoter methylation had a similar OR in intestinal gastric cancer and nonintestinal gastric cancer under a fixed-effects model (I2 = 0.0%, OR = 0.97, 95% CI = 0.72–1.32, P = 0.863), which suggested that DAPK promoter methylation was not correlated with tumor histology. This evidence concerns the gene DAPK1 and gastric cancer.