A monomeric compound Tanshinone II‐A isolated from S. miltiorrhiza, could inhibit inflammatory responses and provide cardioprotective effects during myocardial infarction by decreasing the expression of tumour necrosis factor‐α, reducing monocyte chemoattractant protein (MCP‐1) and transforming growth factor‐β secretion of cardiac fibroblasts, and suppressing the activation of nuclear transcription factor‐kappa B (NF‐κB) 33, 34. Here, CCL2 is linked to myocardial infarction.