Putative mechanistic pathways are suggested by Mun et al. [14] who reported that fluoxetine induced apoptosis of a HCC line via increased oxidative stress and reduction of mitochondrial membrane potential, while Chen et al. [15] reported that sertraline-induced apoptosis of HCC line is mediated via mitogen-activated protein kinase pathway. The gene discussed is WNK2; the disease is hepatocellular carcinoma.