SLC7A2 and infection: Furthermore, loss of colonic goblet cells is another characteristic in mice infected with C. rodentium [23]; when assessed by using periodic acid–Schiff staining, we found that infection resulted in a 47.5 ± 6.5% loss of goblet cells in WT mice compared to only a 25.6 ± 5.3% loss in Slc7a2–/–mice (S3 Fig).