IL1B and type 2 diabetes mellitus: Expression of mRNA encoding several cytokines, including IFN-γ, TNF-β, and IL-1β, was higher in Wistar rats at 1 and 3 weeks p.i., but higher in GK/Jcl rats by 12 weeks p.i. Podell et al. [11] reported increased TB susceptibility in guinea pigs with T2DM induced by low dose STZ plus a high-fat, high-sucrose diet.