The frequency of IFN-γ- (1.7-fold, p = 0.0002; Fig 9A), IL-2- (2.1-fold, p = 0.0001; Fig 9A and 9B), TNF-α- (1.6-fold, p = 0.0005; Fig 9A), and IL-17A- (2-fold, p = 0.0004; Fig 9A) producing cells was significantly higher in diabetic than in non-diabetic pulmonary TB patients. Here, IFNG is linked to pulmonary tuberculosis.