MRC1 and hyperinsulinemic hypoglycemia, familial, 4: As mentioned above, MMR deficiency causes cellular resistance against various antineoplastic agents such as cyclophosphamide, doxorubicin (Drummond et al. 1996; Fink et al. 1998) and etoposide (Aebi et al. 1997; Fink et al. 1998).