NLGN4X and Intellectual disability: In addition, three haplotype sets in NLGN4X (rs3810686(T), rs1882260(C)), (rs6638575(G), rs3810686(T), rs18882260(T)) and (rs6638575(A), rs3810686(C), rs18882260(C)), have been positively associated with nonspecific mental retardation (Intelligence Quotients IQs < 70) and social disability scores ≤ 8 [36] and genetic variants in NLGN4X also have a significant effect on male cognitive abilities, highlighting the role of neuroligins in psychiatric conditions [37].