CDH1 and Familial gastric cancer: Although decreased expression of E‐cadherin is known in the diffuse‐type gastric cancer in general, aberrant expression of this gene is widely present in EOGC regardless of histological type 24, but also correlated significantly with the diffuse and mixed types in the familial gastric cancer (FGC) 25, suggesting a role of E‐cadherin in FGC tumorigenesis.