These results revealed an adjuvant effect of TLR2 and TLR4 agonists on IL-6, TNF, IL-10 and IL-13 secretion, while TLR7/8 agonists increased IL-6, TNF, IL-10 and IFN-γ production by PBMCs of SS patients. Here, TLR4 is linked to synovial sarcoma.