FBP1 and infection: To further address whether the cleavage of FBP1 is important for EV71 virus yield in infected cells, shNC or shFBP1 RD cells that expressing vector control, FBP1R or cleavage-resistant FBP1(G371)R were infected with EV71 at a m.o.i. of 40, and the viral titers during the course of infection were measured by plaque assays.