Western blot analysis performed in MCF10DCIS.com transduced cells revealed that the reduction of CHD4 did not increase TP53 protein level and its Serine-15 phosphorylation at different time points (2, 3 and 5 days after infection), but it determined a substantial up-regulation of CDKN1A protein level (Figure 4C) since the early time point (2 days since infection) of the experimental assay. This evidence concerns the gene CHD4 and infection.