TNFAIP3 and rheumatoid arthritis: In the overall analysis, we detected significant association (Table 2) between TNFAIP3 gene rs10499194, rs13207033 polymorphisms with decreased RA risk (rs10499194, TT vs. CT+CC: OR, 0.80; 95% CI, 0.74–0.88, P < 0.001, Figure 2; rs13207033, GA vs. GG: OR, 0.88; 95% CI, 0.79–0.99, P = 0.034, Figure 3).