Recent genetic studies have linked human MEF2C to a syndromic form of intellectual disability with autistic features, and single-nucleotide polymorphisms (SNPs) near MEF2C produce significant risk for SCZ (Paciorkowski et al., 2013; Mikhail et al., 2011; Novara et al., 2010; Le Meur et al., 2010; Cardoso et al., 2009; Engels et al., 2009), which highlight the importance of this gene for normal brain development and function. This evidence concerns the gene MEF2C and Intellectual disability.