When the participants were dichotomised based on diabetes status, the serum levels of Ang-1 [42.7 (27–57.1) vs. 37.2 (28.1–43) nmol/ml, p = 0.027], Ang-2 [0.85 (0.48–1.25) vs. 0.6 (0.27–1) nmol/ml, p = 0.011] and VEGF [75.7 (30.7–208.1) vs. 50.2 (17.4–110.1) pmol/ml, p = 0.022] were higher in T2DM patients than non-diabetes participants respectively. Here, ANGPT1 is linked to type 2 diabetes mellitus.