In contrast, apoptosis of p53-deficient lymphomas can be induced by amylin acting via the CTR.32,33 Consistent with this finding, induction of apoptosis by CT has also been observed in HEK 293 cells transfected with CTR.34 CTR is also expressed in quiescent muscle satellite cells where it acts to protect these cells from apoptosis,35 although the ligand is unknown. Here, CALCR is linked to lymphoma.