Infiltration of TBET+ cells (T-box transcription factor TBX21, a marker of type 1 T-cells) can also predict improved disease free survival (DFS) in all breast cancer subtypes with breast cancer patients with tumors containing < 30 TBET+ cells having decreased DFS as compared to patients with tumors containing ≥30 TBET+ cells (RR 5.62 95 % CI 1.48–50.19 p = 0.0027 n = 617) [17]. This evidence concerns the gene TBX21 and breast carcinoma.