RUNX3 and Alzheimer disease: Additionally, Esparza-Gordillo et al. analyzed data in the public repository and validated selected markers in three different sets of cases and controls, and identified 4 SNPs, rs2040704 (RAD50), rs10903122 (RUNX3), rs2292239 (ERBB3) and rs2228145 (IL6R), as new susceptibility genes for AD.