To explore the possible mechanism responsible for the growth inhibition effect of DBCCR1-003, we performed flow cytometry assay, and found that knock-in DBCCR1-003 induced G0/G1 cell-cycle arrest and cell apoptosis in T24 cells, indicating that BC cell growth mediated by DBCCR1-003 may be related to the regulation of cell cycle and apoptosis. Here, BRINP1 is linked to breast cancer.