FASLG and systemic lupus erythematosus: Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by the production of autoantibodies targeting nuclear and membrane molecules [i.e., antinuclear antibodies (ANA) and antiphospholipid antibodies (aPL)] in association with systemic and local inflammatory manifestations as well as premature vascular disease1, 2, 3.