CYP39A1 and pheochromocytoma: However, some genes associated with steroid, organic hydroxy compound, and alcohol-related processes that were upregulated in ZG samples from phaeochromocytoma patients (eg, CYP11B2, CYP39A1, PLA2G1B, and SULT1E1), were not significantly upregulated in ZG samples from adrenals with an APA (Table S12).