Compared to control, as one of the Th1-associated chemokine receptors, CCR3 mRNA levels in active ITP decreased (0.63 ± 0.07 vs 1.01 ± 0.04); after treatment with HD-DXM, CXCR3 expression in responders increased significantly (1.20 ± 0.12, Fig. 3c). This evidence concerns the gene CXCR3 and autoimmune thrombocytopenic purpura.