Guillain-Barré syndrome (GBS) was suspected, though anti-ganglioside antibodies (GM1-IgG, GM1-IgM, GQ1b-IgG, GQ1b-IgM, GD1a-IgG, GD1a-IgG, GD1b-IgG, GD1b-IgM) were negative. Here, CD40LG is linked to Guillain-Barre syndrome.