ADGRD1 and glioblastoma: Histology at the time of death for scramble mice showed expansive and brain-infiltrating tumor formation in mice injected with scramble control GBM cells (Figure 6c, upper panel), whereas in animals injected with GPR133-KD no. 1 cells, we only found few scattered human cells, identified by human nuclear antigen staining at the site of the injection (Figure 6c, arrow in lower panel).