The complex process of spheroid implantation involves integrin/talin-dependent activation of myosin to produce traction force to displace mesothelial cells from underneath a tumor spheroid.9 To determine if SUSD2 affects spheroid implantation in HGSOC, we performed in vitro mesothelial clearance assays using OVCAR3, OVSAHO and KURAMOCHI stable cell lines. Here, SUSD2 is linked to neoplasm.