SUSD2 and neoplasm: In a recent publication, our laboratory analyzed the function of SUSD2 in breast tumorigenesis.15 Using in vitro phenotypic assays, we showed that overexpression of SUSD2 in MDA-MB-231 cells increased invasion and contributed to an immune evasion mechanism through induction of apoptosis of T cells.15 Furthermore, using a syngeneic mouse model, we revealed that mice with SUSD2-expressing tumors had poorer survival and increased tumor growth rates compared with mice with tumors not expressing SUSD2. 15