Combination of the data from the first and second phase studies further strengthened the association between IL-37/rs3811047 and BD (GG genotype: Pc = 7.27 × 10−8, OR = 1.693; AG genotype: Pc = 3.67 × 10−6, OR = 0.616; G allele: Pc = 7.68 × 10−8, OR = 1.584) and the observed association between IL-18RAP/rs2058660 and BD (AA genotype: Pc = 1.27 × 10−5, OR = 0.620; A allele: Pc = 5.94 × 10−6, OR = 0.750) (Table 2). Here, IL18RAP is linked to Behcet disease.