Among these genes, DMRTA2 encodes a transcription factor involved in human female germ cell development;21KCNG2 encodes a potassium channel subunit whose altered expression has been associated with malignant glial tumors;22 and PSMD10 encodes a regulatory subunit of the 26S proteasome. The gene discussed is KCNA3; the disease is malignant glioma.