MAP2K7 and schizophrenia: MAP2K7 sequence variants show a strong genetic association with schizophrenia (Winchester et al. 2012), and other kinases closely involved in MKK7-JNK signalling have been detected as potentially associated with schizophrenia in recent GWAS (Morris and Pratt 2014; Schizophrenia Working Group of the Psychiatric Genomics 2014).