For example, pre-incubation of KIR+ NK cells (from an alloreactive donor) with CCR7+ HLA class I-deficient cells, before their adoptive transfer to the patient, would allow CCR7+ alloreactive NK cells to be rapidly recruited to lymph nodes and to eliminate the leukemia cells residual after conditioning and patient’s DC/T cells (78) (Figure 2). The gene discussed is CCR7; the disease is leukemia.