There are several possible mechanisms by which hepatic steatosis may contribute to the risk of CVDs including oxidative stress, inflammation, dyslipidemia, ischemia reperfusion injury, visceral fat, low adiponectin, ectopic adipose tissue distribution, endothelial dysfunction and postprandial dyslipidemia (Liu and Lu, 2014). The gene discussed is ADIPOQ; the disease is metabolic syndrome.