Further adjustment for alcohol intake, smoking status, physical activity, prevalent CVD, serum TC, use of serum lipid-reducing medications, SBP and treatment for hypertension, and CRP concentration did not materially affect the association between DHEA and incident type 2 diabetes (per 1 unit natural log-transformed, HR 0.76, 95% CI 0.67, 0.87), but it abolished the association between DHEAS and type 2 diabetes (Table 2). The gene discussed is CRP; the disease is type 2 diabetes mellitus.