Hypocomplementaemia was also found to be associated with a number of autoantibodies typically associated with other rheumatic diseases, which included anti-RNP (4.5 % vs. 1.2 %, p = 0.001), anti-Ro (10.8 % vs. 5.2 %, p = 0.001), anti-Sm (1.5 % vs. 0.2 %, p = 0.016) and anti-phospholipid (31.3 % vs. 24.0 %, p = 0.02) antibodies. This evidence concerns the gene RNPC3 and rheumatic disorder.