NFE2L2 and neoplasm: In the training set (METABRIC dataset, consisting of 1942 patients) we identified associations between NFE2L2 mRNA expression levels and the patient’s age (P < 0.001), tumour histology (P = 0.001), menopausal status (P = 0.003) and HER2 status (P = 0.041) (Table 1A).