Upon multivariable analysis, RSE duration (OR 1.10; 95 % CI: 1.00–1.28; p = 0.044), sepsis (OR 10.2; 95 % CI: 1.25–82.46; p = 0.030), and STESS ≥ 3 (OR 11.92; 95 % CI: 1.93–73.56; p = 0.008) – but not use of CLB (OR 1.80; 95 % CI: 0.35–9.13; p = 0.481) – were independently related to outcome. This evidence concerns the gene CLYBL and Sepsis.