Multivariate analysis showed that T classification (p = 0.036), N classification (p = 0.003), distant metastasis (p < 0.001), relapse (p = 0.002) and CFTR expression level (p = 0.003) were independent prognostic factors for NPC (Table 2, right panel). The gene discussed is CFTR; the disease is nasopharyngeal carcinoma.