LEP and posterior cortical atrophy: On the contrary, the variants of LEP rs1349419 (allele contrast: OR 0.865, 95%CI 0.757-0.988), LEP rs12535708 (allele contrast: OR 0.869, 95%CI 0.757-0.998), LEP rs12535747 (allele contrast: OR 0.860, 95%CI 0.749-0.987) and LEP D7S1875 (allele contrast: OR 0.573, 95%CI 0.347-0.945) were associated with decreased risk of total PCa (Table 3).