Three SNPs (ENO1 rs2274971A > G, PFKM rs11168417C > T, and PDK2 rs3785921G > A) were significantly associated with OS and/or DFS in squamous cell carcinoma (SCC) but not in adenocarcinoma (AC), whereas PFKP rs1132173C > T exhibited a significant association with survival outcomes in AC but not in SCC (Table 3 and Supplementary Figure 1A–D). Here, PFKM is linked to squamous cell carcinoma.