KRAS and metastatic malignant neoplasm in the lymph nodes: In patient 1, tumour 3 (T3) and a lymph node metastasis shared 52 (26%) of 198 mutations, including a KRAS (p.G12V) mutation and a STAG2 nonsense mutation (p.R305X), suggesting that the tumour metastasized to the lymph node (Figs 1 and 2).